WD Repeat-Containing Protein 68 (WDR68) Antibody

WDR68 is involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

Target	WD Repeat-Containing Protein 68 (WDR68)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 285-314 amino acids from the C-terminal region of human WDR68.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P61962 (UniProt, ExPASy)
UniProt Secondary AC	B4E039, D3DU14, O15491, Q9DAE4
UniProt Entry Name	DCAF7_HUMAN
KEGG	hsa:10238
String	9606.ENSP00000483236
Molecular Weight	Calculated MW: 38.9 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse DCAF7.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on WD Repeat-Containing Protein 68 (WDR68)

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