Wee1 (pS53) Antibody

This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product.

This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product.

This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.

Target	Wee1 (pS53)
Clonality	Polyclonal
Target Modification	Ser53
Modification	Phosphorylation
Reactivity	Human
Tested Applications	ELISA, IHC, DB
Host	Rabbit
Recommended dilutions	IHC-P: 1/100 - 1/500, DB: 1/500. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S53 of human Wee1.
Isotype	IgG
Form	Liquid
Purification	Purified by protein G affinity chromatography. Then, the antibody fraction was peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody was eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P30291 (UniProt, ExPASy)
UniProt Secondary AC	B3KVE1, D3DQV0
UniProt Entry Name	WEE1_HUMAN
NCBI Accession	NP_001137448.1 NP_003381.1
KEGG	hsa:7465
String	9606.ENSP00000402084
Molecular Weight	Calculated MW: 71.6 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Rat WEE1.
Availability	Please enquire.
Note	This product is for research use only.

Research Articles on Wee1 (pS53)

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