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Wee1 (pS123) Antibody
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Catalogue No: abx031927
Price:
US$290.00
(Size: 80 µl)
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This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.
Research Articles on Wee1 (pS123)
| Target | Wee1 (pS123) |
| Clonality | Polyclonal |
| Target Modification | Ser123 |
| Modification | Phosphorylation |
| Reactivity | Human |
| Tested Applications | ELISA, IHC, DB |
| Host | Rabbit |
| Recommended dilutions | IHC-P: 1/50 - 1/100, DB: 1/500. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S123 of human Wee1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by protein G affinity chromatography. Then, the antibody fraction was peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody was eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P30291 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KVE1, D3DQV0 |
| UniProt Entry Name | WEE1_HUMAN |
| NCBI Accession | NP_001137448.1 NP_003381.1 |
| KEGG | hsa:7465 |
| String | 9606.ENSP00000402084 |
| Molecular Weight | Calculated MW: 71.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
