Protein Wnt-5a (WNT5A) Antibody

WNT5A: wingless-type MMTV integration site family, member 5A.Entrez Protein: NP_003383.The WNT gene family consists of structurally related genes which encode secreted signaling proteins.These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis.This gene is a member of the WNT gene family.It encodes a protein which shows 98%, 98% and 87% amino acid identity to the mouse, rat and the xenopus Wnt5A protein, respectively.The experiments performed in Xenopus laevis embryos identified that human frizzled-5 (hFz5) is the receptor for the Wnt5A ligand and the Wnt5A/hFz5 signaling mediates axis induction.

Target	Protein Wnt-5a (WNT5A)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, IHC
Host	Mouse
Recommended dilutions	ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of WNT5A expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P41221 (UniProt, ExPASy)
UniProt Secondary AC	A8K4A4, Q6P278
UniProt Entry Name	WNT5A_HUMAN
Gene Symbol	WNT5A
GeneID	7474
OMIM	164975
HGNC	12784
KEGG	hsa:7474
Ensembl	ENSG00000114251
String	9606.ENSP00000264634
Molecular Weight	42.3 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Protein Wnt-5a (WNT5A)

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