NEDD4-Like E3 Ubiquitin-Protein Ligase WWP2 (WWP2) Antibody

WWP2 Antibody is a Rabbit Polyclonal antibody against WWP2. WWP2(WW domain-containing protein 2) is also named as AIP2 and belongs to the NEDD4-like protein family. It functions as an E3 ubiquitin ligase for PTEN that plays a vital role in tumour-cell survival and is also involved in regulating transcription, embryonic stem-cell fate, cellular transport and T-cell activation processes(PMID:21532586).WWP2, which specifically interacted with ES cell-specific transcription factor Oct-4 and promoted its ubiquitination both in vitro and in vivo, is a ubiquitously expressed protein and exists in both cytoplasmic and nuclear compartments in ES cells(PMID:15047715). This antibody is specific to WWP2.

Target	NEDD4-Like E3 Ubiquitin-Protein Ligase WWP2 (WWP2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 151-400 of human WWP2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O00308 (UniProt, ExPASy)
UniProt Entry Name	WWP2_HUMAN
Gene Symbol	WWP2
GeneID	11060
NCBI Accession	NP_001257383.1
KEGG	hsa:11060
String	9606.ENSP00000352069
Molecular Weight	Calculated MW: 99 kDa Observed MW: 105 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on NEDD4-Like E3 Ubiquitin-Protein Ligase WWP2 (WWP2)

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