NEDD4-Like E3 Ubiquitin-Protein Ligase WWP2 (WWP2) Antibody

Catalogue No: abx001912
Price: £120.00
(Size: 20 µl)
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WWP2 Antibody is a Rabbit Polyclonal antibody against WWP2. WWP2(WW domain-containing protein 2) is also named as AIP2 and belongs to the NEDD4-like protein family. It functions as an E3 ubiquitin ligase for PTEN that plays a vital role in tumour-cell survival and is also involved in regulating transcription, embryonic stem-cell fate, cellular transport and T-cell activation processes(PMID:21532586).WWP2, which specifically interacted with ES cell-specific transcription factor Oct-4 and promoted its ubiquitination both in vitro and in vivo, is a ubiquitously expressed protein and exists in both cytoplasmic and nuclear compartments in ES cells(PMID:15047715). This antibody is specific to WWP2.

Target WWP2
Clonality Polyclonal
Reactivity Human
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein of human WWP2.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O00308 (UniProt, ExPASy)
UniProt Entry Name WWP2_HUMAN
Gene Symbol WWP2
GeneID 11060
KEGG hsa:11060
String 9606.ENSP00000352069
Molecular Weight Calculated MW: 35 kDa, 51 kDa, 86 kDa, 98 kDa
Observed MW: 105 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on WWP2

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