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X-Ray Repair Cross Complementing 1 (XRCC1) Antibody

Catalogue No: abx000721
Price: £120.00
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X-Ray Repair Cross Complementing 1 (XRCC1) Antibody

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XRCC1 Antibody is a Rabbit Polyclonal antibody against XRCC1. The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Target XRCC1
Clonality Polyclonal
Reactivity Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human XRCC1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P18887 (UniProt, ExPASy)
UniProt Secondary AC Q6IBS4, Q9HCB1
UniProt Entry Name XRCC1_HUMAN
Gene Symbol XRCC1
GeneID 7515
KEGG hsa:7515
String 9606.ENSP00000262887
Molecular Weight Calculated MW: 69 kDa
Observed MW: 70 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on X-Ray Repair Cross Complementing 1 (XRCC1) Antibody

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