X-Ray Repair Cross Complementing 1 (XRCC1) Antibody

XRCC1 Antibody is a Rabbit Polyclonal antibody against XRCC1. The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Target	X-Ray Repair Cross Complementing 1 (XRCC1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/100 - 1/500, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 480-633 of human XRCC1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P18887 (UniProt, ExPASy)
UniProt Secondary AC	Q6IBS4, Q9HCB1
UniProt Entry Name	XRCC1_HUMAN
Gene Symbol	XRCC1
GeneID	7515
NCBI Accession	NP_006288.2
KEGG	hsa:7515
String	9606.ENSP00000262887
Molecular Weight	Calculated MW: 69 kDa Observed MW: 82 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on X-Ray Repair Cross Complementing 1 (XRCC1)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue