X-Ray Repair Cross Complementing 3 (XRCC3) Antibody

XRCC3 Antibody is a Rabbit Polyclonal antibody against XRCC3. This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008].

Target	X-Ray Repair Cross Complementing 3 (XRCC3)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 62-346 of human XRCC3.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O43542 (UniProt, ExPASy)
UniProt Secondary AC	O43568, Q9BU18
UniProt Entry Name	XRCC3_HUMAN
Gene Symbol	XRCC3
GeneID	7517
NCBI Accession	NP_001093588.1
KEGG	hsa:7517
String	9606.ENSP00000451974
Molecular Weight	Calculated MW: 38 kDa Observed MW: 37 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on X-Ray Repair Cross Complementing 3 (XRCC3)

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