XRCC3 Antibody is a Rabbit Polyclonal antibody against XRCC3. This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008].
| Target |
XRCC3 |
| Clonality |
Polyclonal |
| Reactivity |
Human, Mouse, Rat |
| Tested Applications |
WB, IHC, IF/ICC |
| Host |
Rabbit |
| Recommended dilutions |
WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation |
Unconjugated |
| Immunogen |
Recombinant protein of human XRCC3. |
| Isotype |
IgG |
| Form |
Liquid |
| Purification |
Affinity purified. |
| Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC |
O43542 (UniProt,
ExPASy)
|
| UniProt Secondary AC |
O43568, Q9BU18 |
| UniProt Entry Name |
XRCC3_HUMAN |
| Gene Symbol |
XRCC3 |
| GeneID |
7517
|
| KEGG |
hsa:7517
|
| String |
9606.ENSP00000451974
|
| Molecular Weight |
Calculated MW: 37 kDa
Observed MW: 37 kDa |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| Concentration |
> 1 mg/ml |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
Research Articles on X-Ray Repair Cross Complementing 3 (XRCC3) Antibody
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