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X-Ray Repair Cross-Complementing Protein 4 (XRCC4) Antibody
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Catalogue No: abx001409
Price:
US$217.50
(Size: 20 µl)
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XRCC4 Antibody is a Rabbit Polyclonal antibody against XRCC4. The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq, Sep 2008].
Research Articles on X-Ray Repair Cross-Complementing Protein 4 (XRCC4)
| Target | X-Ray Repair Cross-Complementing Protein 4 (XRCC4) |
| Clonality | Polyclonal |
| Reactivity | Human, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to XRCC4. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13426 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K3X4, Q9BS72, Q9UP94 |
| UniProt Entry Name | XRCC4_HUMAN |
| Gene Symbol | XRCC4 |
| GeneID | 7518 |
| NCBI Accession | NP_001304941.1 |
| KEGG | hsa:7518 |
| String | 9606.ENSP00000421491 |
| Molecular Weight | Calculated MW: 38 kDa Observed MW: 55 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |