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X-Ray Repair Cross Complementing 6 (XRCC6) Antibody

Catalogue No: abx000886
Price: £120.00
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X-Ray Repair Cross Complementing 6 (XRCC6) Antibody X-Ray Repair Cross Complementing 6 (XRCC6) Antibody X-Ray Repair Cross Complementing 6 (XRCC6) Antibody X-Ray Repair Cross Complementing 6 (XRCC6) Antibody X-Ray Repair Cross Complementing 6 (XRCC6) Antibody X-Ray Repair Cross Complementing 6 (XRCC6) Antibody X-Ray Repair Cross Complementing 6 (XRCC6) Antibody X-Ray Repair Cross Complementing 6 (XRCC6) Antibody X-Ray Repair Cross Complementing 6 (XRCC6) Antibody X-Ray Repair Cross Complementing 6 (XRCC6) Antibody X-Ray Repair Cross Complementing 6 (XRCC6) Antibody X-Ray Repair Cross Complementing 6 (XRCC6) Antibody X-Ray Repair Cross Complementing 6 (XRCC6) Antibody X-Ray Repair Cross Complementing 6 (XRCC6) Antibody X-Ray Repair Cross Complementing 6 (XRCC6) Antibody X-Ray Repair Cross Complementing 6 (XRCC6) Antibody X-Ray Repair Cross Complementing 6 (XRCC6) Antibody

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XRCC6 Antibody is a Rabbit Polyclonal antibody against XRCC6. X-ray repair cross-complementing protein 6 (XRCC6) gene encodes subunit p70 of the p70/p80 autoantigen which has a role in DNA repair or transposition. DNA helicase II complex binds preferentially to fork-like ends of double-standed DNA in a cell cycle-dependent manner, which may be mediated by XRCC6. XRCC6/5 can form a heterdimer, which function as a regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit PRKDC to DNA, and also it can stablize broken DNA ends and bringing them together. Otherwise, XRCC5/6 heterdimer together with APEX1 can negatively regulate of transcription.

Target XRCC6
Clonality Polyclonal
Reactivity Human, Mouse, Rat, Monkey
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human XRCC6.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P12956 (UniProt, ExPASy)
UniProt Secondary AC B1AHC8, Q6FG89, Q9UCQ2, Q9UCQ3
UniProt Entry Name XRCC6_HUMAN
Gene Symbol XRCC6
GeneID 2547
KEGG hsa:2547
String 9606.ENSP00000352257
Molecular Weight Calculated MW: 65 kDa, 69 kDa
Observed MW: 70 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on X-Ray Repair Cross Complementing 6 (XRCC6) Antibody

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