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YAP1 (pS127) Antibody
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Catalogue No: abx000521
Price:
£120.00
(Size: 20 µl)
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YAP1 (pS127) Antibody is a Rabbit Polyclonal antibody against YAP1 (pS127). This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
Research Articles on YAP1 (pS127)
| Target | YAP1 (pS127) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Synthetic peptide. A phospho specific peptide corresponding to residues surrounding S127 of human YAP1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P46937 (UniProt, ExPASy) |
| UniProt Entry Name | YAP1_HUMAN |
| Gene Symbol | YAP1 |
| GeneID | 10413 |
| KEGG | hsa:10413 |
| String | 9606.ENSP00000478927 |
| Molecular Weight | Calculated MW: 36 kDa, 48 kDa, 49 kDa, 50 kDa, 52 kDa, 53 kDa, 54 kDa Observed MW: 54 kDa |
| Buffer | PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.5 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
