YAP1 (pS127) Antibody is a Rabbit Polyclonal antibody against YAP1 (pS127). This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
| Target |
YAP1 (pS127) |
| Clonality |
Polyclonal |
| Reactivity |
Human, Mouse, Rat, Monkey |
| Tested Applications |
WB |
| Host |
Rabbit |
| Recommended dilutions |
WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation |
Unconjugated |
| Immunogen |
Synthetic peptide. A phospho specific peptide corresponding to residues surrounding S127 of human YAP1. |
| Isotype |
IgG |
| Form |
Liquid |
| Purification |
Affinity purified. |
| Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC |
P46937 (UniProt,
ExPASy)
|
| UniProt Entry Name |
YAP1_HUMAN |
| Gene Symbol |
YAP1 |
| GeneID |
10413
|
| String |
9606.ENSP00000478927
|
| Molecular Weight |
Calculated MW: 36 kDa, 48 kDa, 49 kDa, 50 kDa, 52 kDa, 53 kDa, 54 kDa
Observed MW: 54 kDa |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| Concentration |
> 1 mg/ml |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
Research Articles on YAP1 (pS127) Antibody
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