Yes Associated Protein 1 Phospho-Ser127 (YAP1 pS127) Antibody
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Catalogue No: abx000521
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US$232.00
(Size: 20 µl)
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Datasheet SDS
YAP1 (pS127) Antibody is a Rabbit Polyclonal antibody against YAP1 (pS127). This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
Research Articles on Yes Associated Protein 1 Phospho-Ser127 (YAP1 pS127)
| Target | Yes Associated Protein 1 Phospho-Ser127 (YAP1 pS127) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/100 - 1/500, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Synthetic peptide corresponding to YAP1 pS127. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P46937 (UniProt, ExPASy) |
| UniProt Entry Name | YAP1_HUMAN |
| Gene Symbol | YAP1 |
| GeneID | 10413 |
| NCBI Accession | NP_001123617.1 |
| KEGG | hsa:10413 |
| String | 9606.ENSP00000478927 |
| Molecular Weight | Calculated MW: 54 kDa Observed MW: 75 kDa |
| Buffer | PBS, pH 7.3, containing 0.09% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |