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14-3-3 Protein Epsilon (YWHAE) Antibody

Catalogue No: abx000981
Price: £120.00
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YWHAE Antibody is a Rabbit Polyclonal antibody against YWHAE. This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene.

Target YWHAE
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human YWHAE.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P62258 (UniProt, ExPASy)
UniProt Entry Name 1433E_HUMAN
Gene Symbol YWHAE
GeneID 7531
KEGG hsa:753
String 9606.ENSP00000264335
Molecular Weight Calculated MW: 26 kDa, 29 kDa
Observed MW: 29 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on 14-3-3 Protein Epsilon (YWHAE) Antibody

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