14-3-3 Protein Zeta/Delta (YWHAZ) Antibody

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Catalogue No: abx033911
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
YWHAZ belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for the gene. Both variants encode the same protein, however, they are differentially expressed in hematopoietic cells.

Target 14-3-3 Protein Zeta/Delta (YWHAZ)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 216-245 amino acids from human YWHAZ.
Isotype IgG
Form Liquid
Purification Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P63104 (UniProt, ExPASy)
UniProt Entry Name 1433Z_HUMAN
KEGG hsa:7534
String 9606.ENSP00000379287
Molecular Weight Calculated MW: 27.7 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Rat, Cow, Chicken and Sheep YWHAZ.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on 14-3-3 Protein Zeta/Delta (YWHAZ)


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