Zinc Finger And BTB Domain-Containing Protein 7B (ZBTB7B) Antibody
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Catalogue No: abx016024
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US$427.75
(Size: 100 µl)
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Datasheet SDS
ZBTB7B is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors.It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment.Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively.ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes.It may also function as a repressor of fibronectin and possibly other extracellular matrix genes.
Research Articles on Zinc Finger And BTB Domain-Containing Protein 7B (ZBTB7B)
| Target | Zinc Finger And BTB Domain-Containing Protein 7B (ZBTB7B) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human ZBTB7B expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O15156 (UniProt, ExPASy) |
| UniProt Secondary AC | B4E3K5, D3DV83, J3KQQ3, Q68DR2, Q96EP2 |
| UniProt Entry Name | ZBT7B_HUMAN |
| Gene Symbol | ZBTB7B |
| GeneID | 51043 |
| OMIM | 607646 |
| HGNC | 18668 |
| KEGG | hsa:51043 |
| Ensembl | ENSG00000160685 |
| String | 9606.ENSP00000406286 |
| Molecular Weight | 58 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |