Zinc Finger And BTB Domain-Containing Protein 7B (ZBTB7B) Antibody

ZBTB7B is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors.It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment.Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively.ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes.It may also function as a repressor of fibronectin and possibly other extracellular matrix genes.

Target	Zinc Finger And BTB Domain-Containing Protein 7B (ZBTB7B)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, IF/ICC
Host	Mouse
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human ZBTB7B expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O15156 (UniProt, ExPASy)
UniProt Secondary AC	B4E3K5, D3DV83, J3KQQ3, Q68DR2, Q96EP2
UniProt Entry Name	ZBT7B_HUMAN
Gene Symbol	ZBTB7B
GeneID	51043
OMIM	607646
HGNC	18668
KEGG	hsa:51043
Ensembl	ENSG00000160685
String	9606.ENSP00000406286
Molecular Weight	58 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Zinc Finger And BTB Domain-Containing Protein 7B (ZBTB7B)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue