Zinc Finger CCHC-Type And RNA-Binding Motif-Containing Protein 1 (ZCRB1) Antibody
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Catalogue No: abx027100
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Pre-mRNA splicing is catalyzed by the spliceosome. U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5' splice site and branch-point sequence. U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron. The protein encoded by this gene contains a RNA recognition motif. It was identified as one of the protein components of U11/U12 snRNPs. This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns. These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing.
Research Articles on Zinc Finger CCHC-Type And RNA-Binding Motif-Containing Protein 1 (ZCRB1)
| Target | Zinc Finger CCHC-Type And RNA-Binding Motif-Containing Protein 1 (ZCRB1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 184-212 amino acids from the C-terminal region of human ZCRB1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q8TBF4 (UniProt, ExPASy) |
| UniProt Secondary AC | Q6PJX0, Q96TA6 |
| UniProt Entry Name | ZCRB1_HUMAN |
| Gene Symbol | ZCRB1 |
| KEGG | hsa:85437 |
| String | 9606.ENSP00000266529 |
| Molecular Weight | Calculated MW: 24.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Cow and Xenopus ZCRB1. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |