Zinc Finger E-Box-Binding Homeobox 1 (ZEB1) Antibody

Catalogue No: abx001268
Price: £120.00
(Size: 20 µl)
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ZEB1 Antibody is a Rabbit Polyclonal antibody against ZEB1. ZEB1(zinc-finger-enhancer binding protein 1), which is a members of the Zincfinger-Homeobox (ZFH)-family of repressors, acts as a transcriptional repressor that inhibits interleukin-2 (IL-2) gene expression. Depending on the quantity of cDNA and on the cell type, ZEB1 can enhance or repress the promoter activity of the ATP1A1 gene. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. This is a rabbit polyclonal antibody raised against part of the full length of ZEB1 of human.

Target ZEB1
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000, IHC: 1/50 - 1/200, IF/ICC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein of human ZEB1.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P37275 (UniProt, ExPASy)
UniProt Entry Name ZEB1_HUMAN
Gene Symbol ZEB1
GeneID 6935
KEGG hsa:6935
String 9606.ENSP00000354487
Molecular Weight Calculated MW: 116 kDa, 122 kDa, 124 kDa
Observed MW: 115 kDa, 245 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on ZEB1

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