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Zinc Finger E-Box-Binding Homeobox 1 (ZEB1) Antibody

Catalogue No: abx001268
Price: £120.00
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Zinc Finger E-Box-Binding Homeobox 1 (ZEB1) Antibody

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ZEB1 Antibody is a Rabbit Polyclonal antibody against ZEB1. ZEB1(zinc-finger-enhancer binding protein 1), which is a members of the Zincfinger-Homeobox (ZFH)-family of repressors, acts as a transcriptional repressor that inhibits interleukin-2 (IL-2) gene expression. Depending on the quantity of cDNA and on the cell type, ZEB1 can enhance or repress the promoter activity of the ATP1A1 gene. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. This is a rabbit polyclonal antibody raised against part of the full length of ZEB1 of human.

Target ZEB1
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein of human ZEB1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P37275 (UniProt, ExPASy)
UniProt Entry Name ZEB1_HUMAN
Gene Symbol ZEB1
GeneID 6935
KEGG hsa:6935
String 9606.ENSP00000354487
Molecular Weight Calculated MW: 116 kDa, 122 kDa, 124 kDa
Observed MW: 115 kDa, 245 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Zinc Finger E-Box-Binding Homeobox 1 (ZEB1) Antibody

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