Leucine-Zipper Protein Kinase (ZPK) Antibody
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Catalogue No: abx033235
Price:
US$326.25
(Size: 80 µl)
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Datasheet SDS
ZPK is a member of serine/threonine protein kinase family. This kinase contains a leucine-zipper domain, and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation.
Research Articles on Leucine-Zipper Protein Kinase (ZPK)
| Target | Leucine-Zipper Protein Kinase (ZPK) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 828-859 amino acids from the C-terminal region of human ZPK. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q12852 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KSS9, G3V1Y2, Q86VQ5, Q8WY25 |
| UniProt Entry Name | M3K12_HUMAN |
| NCBI Accession | NP_001180440.1 NP_006292.3 |
| KEGG | hsa:7786 |
| String | 9606.ENSP00000448689 |
| Molecular Weight | Calculated MW: 93.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |