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Zyxin (ZYX) Antibody

Catalogue No: abx001747
Price: £120.00
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Zyxin (ZYX) Antibody

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ZYX Antibody is a Rabbit Polyclonal antibody against ZYX. Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.

Target ZYX
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human ZYX.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q15942 (UniProt, ExPASy)
UniProt Secondary AC A4D2G6, B4DQX7, Q6I9S4
UniProt Entry Name ZYX_HUMAN
Gene Symbol ZYX
GeneID 7791
KEGG hsa:7791
String 9606.ENSP00000324422
Molecular Weight Calculated MW: 45 kDa, 61 kDa
Observed MW: 78 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Zyxin (ZYX) Antibody

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