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SARS-CoV-2 Spike Protein RBD (N450K Mutation)
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Catalogue No: abx620011
Price:
US$333.50
(Size: 50 µg)
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Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) Spike Protein Receptor-Binding Domain (RBD) is a recombinant protein expressed in Mammalian cells. The SARS-CoV-2 Spike Protein (S protein) is a viral protein that allows the entry of SARS-CoV-2 into human cells. The protein forms trimers on the viral capsid and binds to human Angiotensin Converting Enzyme 2 (ACE2) located on the cell surface. The protein has a cleavage site between the Spike Protein and S2 subunits that is targeted by the human enzyme Furin, and it may also cause the development of a syncytium (cell fusion). Antibodies to S protein can prevent viral entry as well as target the virus for further immune action. The N450K mutation is present in the B.1.36 variant first identified in Andhra Pradesh, India.
Research Articles on SARS-CoV-2 Spike Protein RBD (N450K Mutation)
| Target | SARS-CoV-2 Spike Protein RBD (N450K Mutation) |
| Research Area | Infection Immunity |
| Target Modification | Asn450Lys |
| Modification | Mutation |
| Origin | Virus |
| Expression | Recombinant |
| Tested Applications | SDS-PAGE |
| Host | HEK293 cells |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Form | Lyophilized |
| Purity | > 90% (SDS-PAGE) |
| Reconstitution | Reconstitute in ddH2O to a concentration of 1 mg/ml. |
| Storage | Store between -20°C and -80°C. Avoid repeated freeze/thaw cycles. |
| NCBI Accession | YP_009724390.1 |
| Molecular Weight | Observed MW: 35 kDa |
| Tag | C-terminal His tag |
| Buffer | Prior to lyophilization: PBS, pH 7.5. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
