+44 (0) 1223 755950
+1 832 327 7413
SARS-CoV-2 Spike Protein RBD (Omicron B.1.1.529 Variant)
REQUEST MORE INFO
Catalogue No: abx620026
Price:
US$333.50
(Size: 50 µg)
Orders to United States ship from United States
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) Spike Protein Receptor-Binding Domain (RBD) is a recombinant protein expressed in Mammalian cells. The SARS-CoV-2 Spike Protein (S protein) is a viral protein that allows the entry of SARS-CoV-2 into human cells. The protein forms trimers on the viral capsid and binds to human Angiotensin Converting Enzyme 2 (ACE2) located on the cell surface. The protein has a cleavage site between the Spike Protein and S2 subunits that is targeted by the human enzyme Furin, and it may also cause the development of a syncytium (cell fusion). Antibodies to S protein can prevent viral entry as well as target the virus for further immune action. The B.1.1.529 (Omicron) variant was identified in South Africa in November 2021. It possess a large number of mutations (G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493K, G496S, Q498R, N501Y, Y505H) which appear to increase the risk of reinfection compared to other variants of concern.
Research Articles on SARS-CoV-2 Spike Protein RBD (Omicron B.1.1.529 Variant)
| Target | SARS-CoV-2 Spike Protein RBD (Omicron B.1.1.529 Variant) |
| Research Area | Infection Immunity |
| Target Modification | Gly339Asp, Ser371Leu, Ser373Pro, Ser375Phe, Lys417Asn, Asn440Lys, Gly446Ser, Ser477Asn, Thr478Lys, Glu484Ala, Gln493Lys, Gly496Ser, Gln498Arg, Asn501Tyr, Tyr505His |
| Modification | Mutation |
| Origin | Virus |
| Expression | Recombinant |
| Tested Applications | SDS-PAGE |
| Host | Mammalian cells |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Form | Lyophilized |
| Purity | > 90% (SDS-PAGE) |
| Reconstitution | Reconstitute in ddH2O to a concentration of 1 mg/ml. |
| Storage | Store between -20°C and -80°C. Avoid repeated freeze/thaw cycles. |
| NCBI Accession | YP_009724390.1 |
| Molecular Weight | Observed MW: 35 kDa |
| Sequence | The exact sequnce is proprietary. |
| Tag | N-terminal His tag |
| Buffer | Prior to lyophilization: PBS, pH 7.5. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
